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讲师
李志明
来源:     日期:2018-09-03     浏览数:     【 字体:

李志明 现任华中科技大学同济医学院讲师。近年来在Frontiers in Pharmacology, Scientific reports, Cell death discovery,BMJ open, EBioMedicine等知名学术期刊上发表多篇学术论文,授权2项专利,目前单篇文章的最多引用次数达26,累计引用次数超过130次。应邀为国际权威丛书《Methods in Molecular Biology》撰写章节“Integrated Analysis of miRNA and mRNA Expression Profiles to Identify miRNA Targets”。“Genetic predisposition to Parkinson’s disease and cancer”的文章被Global Medical Discovery评选为关键科学论文。


学术经历

2014- 2018:厦门大学,化学生物学,博士;

2016-2017:Wake Forest School of Medicine, Department of Pathology, 博士联合培养;

2010-2013:厦门大学,化学生物学,硕士;


研究方向

个体化诊断与治疗

生殖与转化医学

干细胞与再生医学


学术成果

1.Zhiming Li, Shuai Chen, Yufeng Yang, Zhuang Xuan, Chi-Meng Tzeng. Novel biomarker ZCCHC13 revealed by integrating DNA methylation and mRNA expression data in non-obstructive azoospermia, [J]. Cell death discovery, 2018, 2.


2.Zhiming Li, Zhuang Xuan, Jinxiong Zeng, Chi-Meng Tzeng. Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe Oligozoospermia[J]. Frontiers in physiology, 2017, 8.


3.Zhiming Li, Zaozao Zheng, Jun Ruan, Zhi Li, Xuan Zhuang, Chi-Meng Tzeng. Integrated analysis miRNA and mRNA profiling in patients with severe oligozoospermia reveals MiR-34c-3p downregulates PLCXD3 expression[J]. Oncotarget, 2016.7


4.Zhiming Li#, Li Zhong#, Lu Gong, Wenqing Huang, Xinzhen Shi, Xinlin Zhang, Xingkai An, Qin Lin, Chi-Meng Tzeng. Association study of TREM2 polymorphism rs75932628 with leukoaraiosis or Parkinson’s disease in Han Chinese population [J]. BMJ open, 2016, 6(1): e009499.


5.Zhiming Li#, QingLin#, Wenqing Huang, Chi-Meng Tzeng. Target Gene Capture Sequencing in Chinese Population of Sporadic Parkinson Disease [J]. Medicine, 2015, 94(20): e836.


6.Xuan Zhuang#, Zhiming Li#, Huinuan Lin, Long Gu, QingLin, Zhongxian Lu, Chi-Meng Tzeng*. Integrated miRNA and mRNA expression profiling to identify mRNA targets of dysregulated miRNAs in non-obstructive azoospermia. Scientific reports, 2015, 5:7922.


7.Zhiming Li#, Qing Lin#, Qilin Ma, Congxia Lu, Chi-Meng Tzeng. Genetic predisposition to Parkinson’s disease and cancer. Current cancer drug targets, 2014, 14(3): 310-321.

https://globalmedicaldiscovery.com/key-drug-discovery-articles/genetic-predisposition-parkinsons-disease-cancer/ (reported by Global Medical Discovery)


专利

1.曾骥孟,李志明,顾龙,庄炫. 一种血清miRNA生物标志物组合物与应用, 授权公告号:CN104450702B.

2.曾骥孟,李志明,顾龙,庄炫. 一种血清miRNA生物标志物的应用,授权公告号:CN104450707B;


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